Twenty wheels and tyres have been stolen from six Mercedes Benz Actros vehicles at a business unit on Woodbridge Road in Framlingham.
The items were stolen between noon on Friday, September 13 and 8am, yesterday, Monday, 16 September, after offenders broke into a secure yard where the vehicles were.
Police believe that it would have taken more than one person to move the items, and that tools were needed to lift the vehicles and remove the wheels and tyres.
A substantial vehicle would also have been required to take the stolen items away, police said.
Those with information relating to the theft can contact PC Holly Stranks at Lowestoft Police Station on 101, or Crimestoppers anonymously on 0800 555 111.